Articles
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This handout discusses the growing trend for designer dog breeds – the crossing of pure dog breeds to create dogs that combine “the best of both worlds.” The pros and cons of this practice are highlighted, along with some of the more common designer breeds currently available.
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This handout discusses the need for ensuring your pregnant dog is receiving adequate nutrition to make sure both she and her puppies thrive during this time of increased demands on her body. Feeding and diet suggestions are provided.
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Hemophilia A and B are clotting disorders involving a deficiency of a specific clotting factor (A: Factor VIII, B: Factor IX) needed for appropriate homeostasis. They are caused by a sex-linked recessive genetic mutation. Affected dogs will show inappropriate hemorrhage including bruising, lameness induced by bleeding into joints and body cavity hemorrhage. It can be diagnosed with a slow APTT and demonstrating low levels of the factor involved. Hemophilia A is more common than B and is generally, more severe. Because it is sex-linked recessive, males are more likely to be affected than females but females still act as carriers, so genetic screening is important prior to breeding to prevent this disease.
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Infertility in a female dog is defined as the inability to conceive and deliver viable puppies, even when mated multiple times with a known fertile male surrounding the time of ovulation. This handout outlines the varying causes of infertility in female dogs and how they may be diagnosed and treated.
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Infertility in a male dog is defined as the inability to produce a successful pregnancy in a fertile female, even with multiple breedings near the time of ovulation. The causes of infertility fall under three broad categories: failure to copulate or ejaculate, poor semen quality, and prostatic disease. This handout explains the possible causes in detail, as well as methods to diagnose and treat them.
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Lysosomal storage diseases are a rare collection of conditions that are inherited. Many of them are more prevalent in certain breeds and are seen in the first few months of life. Clinical signs vary depending on the type of disease, but commonly include failure to thrive, incoordination, vision loss, and seizure. Prognosis is usually poor for long-term survival.
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Mastitis is a term used to describe inflammation of a mammary gland. In most cases, mastitis is caused by a bacterial infection. Trauma to the mammary gland, or prolonged periods of milk accumulation without milk removal, can lead to inflammation within the mammary gland. Most dogs with mastitis can be treated on an outpatient basis with oral antibiotics and pain medications, though severe cases may require hospitalization or surgery.
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Miscarriage refers to the death of a fetus during pregnancy, with the most common cause being bacterial infection. Hormonal shifts or abnormalities may also cause miscarriages. In many cases, there are no visible signs of miscarriage. If miscarriage is suspected, ultrasound is used to assess the pregnancy and determine whether the fetuses are alive. Finding a cause for the miscarriage, especially if that cause is a treatable condition, may improve outcomes in future pregnancies.
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Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications. These drugs include several antiparasitic agents (when given at high doses), the antidiarrheal agent loperamide (Imodium®), and several anticancer drugs. The effects of the mutation vary in severity, depending on whether the dog carries one or two copies of the mutation. There is a cheek swab or a commercially-available test that assesses blood samples for the presence of the MDR1 mutation.
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Although uncommon, cats and dogs are at risk for several diseases during the two months of their pregnancy. Pre-eclampsia occurs if the mothers cannot keep up with the demand for calcium to produce bones and milk. Gestational diabetes can occur due to high concentrations of hormones and result in increased drinking, urination, inappropriate weight loss and lethargy. Mastitis is a bacterial infection of one or more mammary glands that is contracted either through the blood (sepsis) or from the external environment from unsanitary conditions and/or injury from babies’ teeth or nails. Retained placentas can occur and will result in lethargy, pyrexia and abnormal vulvar discharge. Be aware of the signs, symptoms and management for all four conditions.
