Articles
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Collie Eye Anomaly (CEA) is a genetic mutation affecting many breeds that causes developmental defects in the eye that can lead to vision deficits or blindness. This defect can be diagnosed by a veterinary ophthalmologist between 6 and 8 weeks of age by visualizing spots of choroidal hypoplasia or a colobomas . It can be associated with microphthalmia or enophthalmia. It can lead to retinal detachment and blindness. Although laser repair of partial retinal detachments can be attempted if detected in early stages, there is generally no treatment for CEA. Vision varies depending on the extent of the lesions and some dogs will become blind. Prevention requires not breeding animals that carry the mutation and this can be achieved through genetic testing of breeding dogs.
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Color dilution alopecia is an autosomal recessive genetic disorder that affects dogs with dilute-colored coats causing hair loss. Some dogs will also be affected by secondary bacterial infections so topical management and pruritus treatments may be needed to improve the dog's comfort. Affected dogs and their relatives should not be bred.
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Corneal dystrophy is a term used to describe several conditions that occur in dogs and cause the corneas to become opaque. There are three major categories of corneal dystrophy: epithelial, stromal, and endothelial. Each is named by the anatomic location of the abnormal tissue and opacity.
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Systemic lymphoma is a very common cancer in dogs, but the cutaneous form is quite rare. Current statistics suggest that cutaneous lymphoma accounts for only about 5% of canine lymphoma cases. The disease can present in a variety of lesions, including ulcers, nodules, red patches, and areas of hair loss and skin scaling. Because not very much is known about canine cutaneous lymphoma, there are no standard treatment protocols and the prognosis is poor.
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Your veterinarian wants to keep your pet healthy and the fact is that people who are better informed take better care of their pets. Do not be overwhelmed by “medicalese”. Try your best to understand this foreign language and if you cannot quite decipher it, ask your veterinarian to speak more plainly.
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If a tooth is unerupted, it is at risk of forming a destructive dentigerous (odontogenic) cyst in the bone. Although unerupted or broken teeth can be painful, dogs rarely show obvious signs of pain. Dentigerous cysts, including and the original tooth must be removed carefully as to avoid compromising the bone, which can easily fracture during the extraction. Dentigerous cysts are preventable if unerupted teeth are addressed early in life.
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Dermatomyositis is hereditary, immune-mediated disease of the skin muscles and blood vessels affecting primarily collies, Shetland Sheepdogs and mixes of these breeds. Other breeds can experience similar disease. Signs are usually first recognized in puppies but can present in young adulthood. Signs include: skin lesions (crusty erosions, patchy alopecia or ulcers) around the eyes, lips, face, ear flaps or tail tip, foot pad lesions; atrophy of chewing muscles or difficulty chewing; stiff gait and megaesophagus in severely affected dogs. Skin biopsies are diagnostic. Treatment involves treating secondary bacterial infections, reducing sun exposure, EFAs, and immunomodulatory medications including tetracycline, niacinamide, pentoxifylline, cyclosporine and corticosteroids. Prognosis varies depending on severity.
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This handout discusses the growing trend for designer dog breeds – the crossing of pure dog breeds to create dogs that combine “the best of both worlds.” The pros and cons of this practice are highlighted, along with some of the more common designer breeds currently available.
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Dexmedetomidine is a sedative/tranquilizer used primarily in cats and dogs as a pre-medication injection for anesthesia or for chemical restraint. It is also used orally in dogs for short-term anxiety management. The most common side effect is a low heart rate. Dexmedetomidine should not be used in patients with severe heart liver or kidney disease. It should be used cautiously in young, old, or weak animals. Consult your veterinary office immediately if you suspect a negative reaction or overdose.
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Discoid Lupus Erythematosus (DLE) is an autoimmune condition that causes skin sloughing particularly around the nose causing scabbing and erosions that can become infected with bacteria. It can also affect the ear flaps, genitals and rarely spread through the entire body. DLE is diagnosed by submitting skin biopsies of affected areas for histopathological analysis. As well as antibiotics to treat secondary bacterial infections, treatment involves suppression of the immune system including tacrolimus or steroid ointments/creams applied to the affected area. Some dogs will need tetracycline and niacinamide or stronger anti-inflammatories such as cyclosporine or corticosteroids. These treatments can be weaned once lesions resolve but flare-ups will likely occur, needing rechecks and repeat therapy. Sun exposure must be minimized as UV light can worsen the disease. If untreated, lesions can develop into squamous cell carcinoma.
