Articles
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The lacrimal duct is part of the nasolacrimal system, a series of narrow tubes that allow tears to drain from the eye into the nose and mouth. This duct can sometimes become blocked or fail to develop properly, resulting in tears overflowing and potentially staining the face below the eye. The clinical signs, diagnosis, and treatment options for the condition are explained in this handout.
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Leaky gut syndrome refers to an increase in the permeability of the intestines. This condition may be caused by any significant insult to the intestines. Acute cases of leaky gut may be caused by infection, trauma, toxins, or medication overdoses. Chronic cases, in contrast, may be caused by food allergies, long-term NSAID use, or other causes. Your veterinarian will perform diagnostic tests to determine the underlying cause of your dog’s intestinal disease and treatments will be targeted at the specific underlying disease that is causing your dog’s leaky gut.
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Leflunomide is an immunomodulating agent used to treat certain immune-mediated conditions in cats and dogs. It is used off label (extra label) in veterinary medicine. Leflunomide comes in a tablet form that may be specially compounded into a liquid. Wear gloves when handling and do not handle if pregnant or nursing.
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Lokivetmab is given by injection and is used on and off label to treat itchiness in dogs. Give as directed. Side effects are uncommon but may include vomiting, diarrhea, sleepiness, lack of appetite, or pain at the injection site. Do not use in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.
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Lorazepam is given by mouth or injection and is used off label to treat behavioral disorders such as fears, phobias, and anxiety, as well as to treat seizures and to stimulate appetite in cats. Common side effects include sleepiness, muscle weakness, incoordination, increased appetite (cats), drooling, aggressive or unusual behavior, increased activity or anxiety, and vocalization. Do not use in pets that are allergic to it or other benzodiazepines, or that have severe breathing problems or liver disease. If a negative reaction occurs, please call your veterinary office.
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Lotilaner is used to treat and prevent flea infestations and treat and control tick infestations in dogs and cats. After being administered to a pet, lotilaner is distributed throughout the body. When fleas or ticks bite the dog or cat, they are exposed to the drug and killed during their blood meal.
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Lung flukes in North America are parasites called Paragonimus kellicotti that infect the lungs of dogs after they have eaten an infected crayfish or rodents that have eaten infected crayfish. Eggs are then released by the parasite into the dog’s sputum to be coughed out or swallowed and released in the feces to continue the life cycle. Lung flukes can be found anywhere in North America but more commonly around the Mississippi River and Great Lakes. Infected dogs can be symptom-free or may develop cough with sometimes bloody mucus, pneumonia, pneumothorax, lethargy and weakness. Diagnosis can include locating eggs of the parasite from feces or mucus from the lungs. X-rays can also reveal cysts in the lungs caused by the parasite. Treatment requires one of 2 commonly used anti-parasitic medications: Praziquantel or Fenbendazole. Although zoonotic, these parasites won’t transmit directly from dogs to humans.
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There are many species of lungworm that can cause respiratory problems in dogs. Infection is acquired through either: ingestion of an intermediate host such as snails or slugs, ingestion of animals that have been infected by eating these animals or depending on the species, from an infected dog by contact with saliva, nasal discharge, or contaminated food and water bowls. Lungworms can be found throughout North America and the world with certain species seen in certain areas. Clincal signs can range from asymptomatic to tachypnea, coughing, sneezing, wheezing, respiratory distress or exercise intolerance. The degree of clinical signs is usually proportional to the strength of the dog’s immune system. Diagnosis involves history, physical exam, x-rays and organism identification through either baermann fecal examination or BAL/bronchoscopy. Treatment involves use of specific antiparasitic drugs for various lengths of time depending on type and severity of infection. Prognosis is good but re-infection can occur.
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Lymphocytic plasmacytic gastroenteritis is a form of inflammatory bowel disease. While the exact cause is not known, it is possible that the intestinal bacteria themselves may be involved in stimulating the immune response. Treatment may include nutrition management, immunosuppressive medications, and dietary supplementation of cobalamin, prebiotics, and probiotics.
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Lymphoma is a cancer of the lymph nodes and lymphatic system. This cancer may be localized to one particular region, or may spread throughout the entire body. Lymphoma is a relatively common cancer, accounting for 15-20% of new cancer diagnoses in dogs. The prognosis for lymphoma varies, depending on various characteristics that can only be determined by specialized testing.
