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  • Mirtazapine is given by mouth or is applied to the skin and is used to treat weight loss in cats and is used off-label to treat inappetence, nausea, and vomiting in cats and dogs. Give as directed. The most common side effects include vocalization, restlessness, vomiting, incoordination, or trembling. Do not use it in pets that are allergic to it or that have recently used an MAOI. If a negative reaction occurs, call your veterinarian.

  • Miscarriage refers to the death of a fetus during pregnancy, with the most common cause being infection. It may also be caused by hormonal shifts or abnormalities. In many cases, there are no visible signs of miscarriage. If miscarriage is suspected, ultrasound is used to assess the pregnancy and determine whether the fetuses are alive. Finding a cause for the miscarriage, especially if that cause is a treatable condition, may improve outcomes in future pregnancies.

  • Miscarriage refers to the death of a fetus during pregnancy, with the most common cause being bacterial infection. Hormonal shifts or abnormalities may also cause miscarriages. In many cases, there are no visible signs of miscarriage. If miscarriage is suspected, ultrasound is used to assess the pregnancy and determine whether the fetuses are alive. Finding a cause for the miscarriage, especially if that cause is a treatable condition, may improve outcomes in future pregnancies.

  • Moxidectin and fluralaner are combined in one topical treatment for use in cats. Moxidectin topical is an avermectin antiparasitic that is used to prevent heartworms and treat intestinal parasites (hookworms and roundworms). Fluralaner is used to treat and prevent fleas and also kills black-legged ticks (deer ticks). Give as directed. Side effects are uncommon but may include hair loss at the application site, itching, vomiting, diarrhea, lethargy, excessive drooling, and dry skin. Moxidectin + fluralaner should not be used in pets that are hypersensitive or allergic to it. Do not use this medication in sick, debilitated, or underweight cats. Use caution in cats with known neurologic disorders. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.

  • Moxidectin is an avermectin antiparasitic that is used to prevent heartworms and treat intestinal parasites. Imidacloprid treats and prevents fleas. These two drugs are combined in one topical product for use in cats, dogs, and ferrets. Use as directed. Side effects are uncommon and usually short-lived, however, if you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Moxidectin + sarolaner + pyrantel is a heartworm disease preventive for dogs that also treats and prevents internal parasites (hookworms and roundworms) and kills fleas and ticks. This medication is given by mouth as a flavored chew tablet. At regular doses, this medication is well-tolerated. Your veterinarian will advise you on the safety of moxidectin + sarolaner + pyrantel use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Pain research has advanced suggesting that a more appropriate choice for managing the chronic pain of OA is multi-modal therapy. Non-steroidal anti-inflammatory drugs are just one of the options leveraged for multi-modal OA management. These include joint supplements, nutraceuticals, nutrition, adjunctive medicines, physical medicine, and changes to the home environment. Every multi-modal treatment plan is tailored to meet the needs of the individual patient and then adjusted as treatment progresses. Once a full multi-modal pain management plan is in place, your veterinarian may be able to lower the dose of NSAID to minimize the risk of an adverse event, and to reserve a full therapeutic dose for any acute inflammatory pain event.

  • Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications. These drugs include several antiparasitic agents (when given at high doses), the antidiarrheal agent loperamide (Imodium®), and several anticancer drugs. The effects of the mutation vary in severity, depending on whether the dog carries one or two copies of the mutation. There is a cheek swab or a commercially-available test that assesses blood samples for the presence of the MDR1 mutation.

  • Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury or strain caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in cats and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.

  • Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury, or strain, caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in dogs and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.

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