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  • Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications. These drugs include several antiparasitic agents (when given at high doses), the antidiarrheal agent loperamide (Imodium®), and several anticancer drugs. The effects of the mutation vary in severity, depending on whether the dog carries one or two copies of the mutation. There is a cheek swab or a commercially-available test that assesses blood samples for the presence of the MDR1 mutation.

  • Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury or strain caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in cats and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.

  • Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury, or strain, caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in dogs and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.

  • This handout discusses muscular dystrophy (MD), primarily in dogs. The cause of the disease is a defect in the proteins found in muscle cells. It is often an inherited disease, usually affecting young dogs. Clinical signs (usually starting as muscle weakness) and diagnosis of the condition are outlined. There is no effective treatment for the condition.

  • When a farrier shoes a horse, accurate placement of each nail through the insensitive epidermal laminae of the hoof is essential. The nail must penetrate deep enough to hold firm, but not deep enough to penetrate the sensitive laminae of the hoof.

  • Polyps are benign fleshy growths that originate from the cells lining a cat's nasal passages, leading to a variety of clinical signs such as sneezing, difficulty breathing, and recurrent ear infections. The various diagnostic tools and treatment approaches are explained in this handout.

  • Navicular 'disease' is really a group of related conditions affecting the navicular bone and associated structures in the foot. There are several possible causes of pain in and around the navicular bone.

  • Colitis is a fairly common problem in dogs manifesting as diarrhea. Dealing with colitis may boil down to working with your veterinarian to find a nutrient profile that allows your dog's gastrointestinal system to function as normally as possible. A nutrient profile which contains a high quality, high digestibility protein, low to moderate fat content, and high digestibility carbohydrates. Fiber may also play a role to benefit the colon of dogs with chronic colitis. Work with your veterinarian to assess your dog's clinical and nutritional history, create a nutritional plan, and then evaluate the success of the plan.

  • Nutritional management can be an effective strategy in the treatment of liver disease when used in combination with appropriate medical therapy. The goals of nutritional management of liver disease focus on controlling the clinical signs as opposed to targeting the underlying cause. Your veterinarian will work with you to help you make the best decisions on behalf of your dog with liver disease.

  • Over 60% of cats in North America are either overweight or obese, so paying attention to the balance between activity and calorie intake is important. Nutrient formulation and portion control are the two most important aspects of weight control. Once you have chosen a formula and have calculated a reasonable daily portion based on calorie density, the best way to stay on track and prevent unwanted weight gain is to combine portion control with regular, formal weigh-ins.

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