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  • Leaky gut syndrome refers to an increase in the permeability of the intestines. This condition may be caused by any significant insult to the intestines. Acute cases of leaky gut may be caused by infection, trauma, toxins, or medication overdoses. Chronic cases, in contrast, may be caused by food allergies, long-term NSAID use, or other causes. Your veterinarian will perform diagnostic tests to determine the underlying cause of your dog’s intestinal disease and treatments will be targeted at the specific underlying disease that is causing your dog’s leaky gut.

  • Lung flukes in North America are parasites called Paragonimus kellicotti that infect the lungs of dogs after they have eaten an infected crayfish or rodents that have eaten infected crayfish. Eggs are then released by the parasite into the dog’s sputum to be coughed out or swallowed and released in the feces to continue the life cycle. Lung flukes can be found anywhere in North America but more commonly around the Mississippi River and Great Lakes. Infected dogs can be symptom-free or may develop cough with sometimes bloody mucus, pneumonia, pneumothorax, lethargy and weakness. Diagnosis can include locating eggs of the parasite from feces or mucus from the lungs. X-rays can also reveal cysts in the lungs caused by the parasite. Treatment requires one of 2 commonly used anti-parasitic medications: Praziquantel or Fenbendazole. Although zoonotic, these parasites won’t transmit directly from dogs to humans.

  • There are many species of lungworm that can cause respiratory problems in dogs. Infection is acquired through either: ingestion of an intermediate host such as snails or slugs, ingestion of animals that have been infected by eating these animals or depending on the species, from an infected dog by contact with saliva, nasal discharge, or contaminated food and water bowls. Lungworms can be found throughout North America and the world with certain species seen in certain areas. Clincal signs can range from asymptomatic to tachypnea, coughing, sneezing, wheezing, respiratory distress or exercise intolerance. The degree of clinical signs is usually proportional to the strength of the dog’s immune system. Diagnosis involves history, physical exam, x-rays and organism identification through either baermann fecal examination or BAL/bronchoscopy. Treatment involves use of specific antiparasitic drugs for various lengths of time depending on type and severity of infection. Prognosis is good but re-infection can occur.

  • Lymphoma is a cancer of the lymph nodes and lymphatic system. This cancer may be localized to one particular region, or may spread throughout the entire body. Lymphoma is a relatively common cancer, accounting for 15-20% of new cancer diagnoses in dogs. The prognosis for lymphoma varies, depending on various characteristics that can only be determined by specialized testing.

  • Lysosomal storage diseases are a rare collection of conditions that are inherited. Many of them are more prevalent in certain breeds and are seen in the first few months of life. Clinical signs vary depending on the type of disease, but commonly include failure to thrive, incoordination, vision loss, and seizure. Prognosis is usually poor for long-term survival.

  • Masticatory muscle myositis (MMM) is an immune system disorder in which the dog's immune system identifies the dog's own muscle tissue as foreign and attacks it.

  • Mastitis is a term used to describe inflammation of a mammary gland. In most cases, mastitis is caused by a bacterial infection. Trauma to the mammary gland, or prolonged periods of milk accumulation without milk removal, can lead to inflammation within the mammary gland. Most dogs with mastitis can be treated on an outpatient basis with oral antibiotics and pain medications, though severe cases may require hospitalization or surgery.

  • Melioidosis is a bacterial infection that is typically associated with tropical regions. The bacteria that causes melioidosis, Burkholderia pseudomallei, is usually found in soil and water. The clinical signs of this condition, along with transmission, diagnosis, treatment, and prognosis, are outlined in this handout.

  • This handout discusses meningitis, an inflammation of the membranes that cover the brain and spinal cord, in dogs. The numerous potential causes, along with the diagnosis, treatment and prognosis of the condition are outlined.

  • Meningoencephalitis is a term referring to inflammation of the brain and the surrounding fluid and tissues. Meningoencephalitis of unknown origin is a term used to describe those cases of meningoencephalitis in which MRI and cerebrospinal fluid analysis indicate the disease but diagnosis through histopathological analysis is not possible. Treatment typically involves immunosuppressant drugs, sometimes with the addition of antibiotics. The prognosis depends on several factors, which are also explained in this handout.

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